北回蔡遠東大哥已回家靜養

文章發表人西域 100 英里耐力跑

感謝mingchu兄的專業介紹, 小弟獲益匪淺!

小弟參與的西域 100 英里耐力跑, 也有抽血檢驗, 做以下的肌肉血液分析

文章發表人 西域 100 英里耐力跑

Muscle Necrosis: It has been found that some degree of muscle cell death in the legs occurs from participation in the Run. The recovery can take several months. This seems to be a bigger problem in runners who become dehydrated or have overexerted themselves. Medical analysis of blood samples taken from Western States runners shows that this occurs to some degree in all runners.

大意是, 缺水或太操, 容易引起腿部肌肉細胞壞死.

此外, 一篇有關跑超馬的生化專論 - Biochemical Strategies for Ultrarunning http://blogs.cybersym.com/ultrarunning-biochem.html, 也提及肌肉細胞壞死,

文章發表人 Biochemical Strategies for Ultrarunning

 Muscle cells, like nerve cells, require appropriate amounts of potassium and sodium ions to produce action potentials, (see Appendix B: The Biochemistry of Nerve Signalling).
Muscle cells also require significant quantities of calcium ions. If
quantities of any of these ions get too far out of balance, the cell
may generate action potentials or calcium signal spikes that have the
wrong magnitude, duration, or propagation. This typically causes the
cell to waste ATP in various ways. When muscle cells use up their
carbohydrate reserves, their mitochondria cannot produce enough ATP,
and contraction does not occur. The muscle cell is said to be fatigued.
A worse situation occurs if ATP runs out during a muscle contraction or
if too much calcium is released into the cytoplasm from failing
mitochondria. Under these conditions the muscle cell becomes locked in
a contracted state. This leads to muscle soreness and tightness. If
enough muscle cells reach this state simultaneously, a muscle cramp
occurs. Muscle cell carbohydrate reserves can be replenished via the
bloodstream (assuming the liver has carbohydrate reserves to transfer
into the blood). However, if an aerobic (high oxidative) muscle cell
(Type I or Type II fatigue resistant muscle) goes too long without
sufficient carbohydrate (tens of minutes), some mitochondria begin to
undergo oxidative damage. Cells contain many mitochondria, but
producing new mitochondria requires hours to days. If enough
mitochondria are damaged, the cell itself begins to experience
oxidative damage and becomes programmed for cell death. Synthesis of
new muscle cells takes days.

大意是, 鈣離子失衡, 易使能量 (ATP) 過度耗費, 肌肉緊縮甚至抽筋, 若加上碳水能源補充不及, 細胞內的引擎 (粒線體), 一一逐漸壞死, 細胞過度氧化, 被迫迅速進入壞死階段, 而產生新細胞卻需要好幾天.